Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04817 |
Syntenin Protein, Human, Recombinant (His)
MDA-9,SYCL,TACIP18,syndecan binding pr... |
Human | E. coli |
Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promotes glioma cell proliferation and invasion by inducing SDCBP expression, which is mediated by JAK2/STAT3 signaling. SDCBP might be an important marker for identifying Triple negative breast cancer (TNBC) cases that are suitable for dasatinib therapy. |